Breadcrumb Home > Thesaurus > S Synonyms of smallpox Find synonyms for: Noun 1. smallpox, variola, variola major, pox usage: a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scars WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of smallpox (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 12 Steps to a New Year New Year's Resolution to Slim Down? Martin Luther King Speeches Books of the Bible: Old Testament Books in Order ✖ Related Content Daily Word Quiz: catalpa Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language