Breadcrumb Home > Thesaurus > E Synonyms of eyestrain Find synonyms for: Noun 1. eyestrain, asthenopia, fatigue, weariness, tiredness usage: a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of eyestrain (Dictionary) TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: demagogue Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language