Breadcrumb Home > Dictionary > Index E endogenous depression: Meaning and Definition of Find definitions for: endog'enous depres'sion Pronunciation: [key] — Psychiatry. Psychiatry. a severe form of depression usually characterized by insomnia, weight loss, and inability to experience pleasure, thought to be of internal origin and not influenced by external events. Also called Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. endogenous endogeny TrendingHere are the facts and trivia that people are buzzing about. Hanukkah Origins of the Christmas Holiday Jewish Holidays, 2010-2030 (A.M. 5770-5791) Western Christian Holidays, 2010-2030 Krampus: The Christmas Devil Kwanzaa ✖ Related Content Daily Word Quiz: anomie Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language